{"id":13582,"date":"2010-02-12T21:07:47","date_gmt":"2010-02-13T01:07:47","guid":{"rendered":"http:\/\/piel-l.org\/blog\/?p=13582"},"modified":"2010-02-13T07:17:39","modified_gmt":"2010-02-13T11:17:39","slug":"caso-de-placa-hipocromica-a-esclarecer-no-abdomen","status":"publish","type":"post","link":"https:\/\/piel-l.org\/blog\/13582","title":{"rendered":"Caso de placa hipocromica a esclarecer, no abdomen"},"content":{"rendered":"<p>Prezados colegas, esta paciente de 66 anos, apresenta ha alguns meses esta placa no abdomen, assintomatica, sem alteracoes de sensibilidade. Aplicou antimicotico, sem melhoras. <br \/>\n Faz uso de antihipertensivos e medicacao para refluxo e colesterol<\/p>\n<p><!--more--><br \/>\n Ha dois anos teve malaria, numa pescaria no Amazonas. <br \/>\n Apresenta esta placa hipocromica, de 4 x 4 , vitiligoide, algo endurecida &#8216;a palpacao como\u00a0 se levemente esclerodermiforme <br \/>\n O histopatologico mostrou:\u00a0 epiderme hiperpigmentada, sem outras anormalidades. Derme sem infiltrado inflamatorio significativo..<\/p>\n<p>COMPATIVEL COM HIPOCROMIA RESIDUAL<\/p>\n<table style=\"width: 300px;\" border=\"0\">\n<tbody>\n<tr>\n<td><a href=\"http:\/\/piel-l.org\/blog\/wp-content\/uploads\/\/2010\/02\/mmpf1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-thumbnail wp-image-13583\" title=\"mmpf1\" src=\"http:\/\/piel-l.org\/blog\/wp-content\/uploads\/\/2010\/02\/mmpf1-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td><a href=\"http:\/\/piel-l.org\/blog\/wp-content\/uploads\/\/2010\/02\/mmpf2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-thumbnail wp-image-13584\" title=\"mmpf2\" src=\"http:\/\/piel-l.org\/blog\/wp-content\/uploads\/\/2010\/02\/mmpf2-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>S\u00f3\u00a0 que a paciente nega totalmente\u00a0qualquer \u00a0traumatismo nesta area, que possa justificar o aspecto residual, por isto coloco para vossa analise e conduta.<\/p>\n<p>Em relacao `a sua malaria, refere que tomou consideravel dose de cloroquina por um periodo nao tao longo, mas foram muitas doses.Vi referencia de hipocromias localizadas correlacionada com uso de antimalarico. Sera&#8217; que este fator foi o \u00abtrigger\u00bb? Seria placa vitiligo-like, por cloroquina?<\/p>\n<p>\u00abAnn Trop Paediatr. 1997 Mar;17(1):45-<\/p>\n<p>Chloroquine-induced vitiligo-like depigmentation.<\/p>\n<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Selvaag%20E%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract\" target=\"_blank\">Selvaag E<\/a>.<\/p>\n<p>Department of Dermatology, Ullevaal Hospital, Oslo, Norway.<\/p>\n<p>A 6-year-old girl of Ethiopian origin with atopic eczema from the age of 2 years is reported. Prior to a visit to her grandparents in Ethiopia, she received 250 mg chloroquine weekly as prophylaxis\u00a0 against malaria. Three weeks later she developed sharply demarcated depigmentation on the face, especially in the peritoneal area. On returning home to Norway, the medication was discontinued and after a few weeks the first repigmentation was noticed. Complete repigmentation was observed 1 year after cessation of chloroquine therapy.\u00bb<br \/>\n obrigado e um abraco, <br \/>\n george<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prezados colegas, esta paciente de 66 anos, apresenta ha alguns meses esta placa no abdomen, assintomatica, sem alteracoes de sensibilidade. Aplicou antimicotico, sem melhoras. Faz uso de antihipertensivos e medicacao para refluxo e colesterol<\/p>\n","protected":false},"author":26,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-13582","post","type-post","status-publish","format-standard","","category-brasilero-venezolana"],"_links":{"self":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/posts\/13582","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/comments?post=13582"}],"version-history":[{"count":0,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/posts\/13582\/revisions"}],"wp:attachment":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/media?parent=13582"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/categories?post=13582"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/tags?post=13582"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}