El art\u00edculo de \u201cElsa H. Spencer,, Hope R. Ferdowsian,, and Neal D. Barnard, Diet and acne: a review of the evidence International Journal of Dermatology 2009, 48, 339\u2013347\u201d, analizan las cinco grandes\u00a0 l\u00edneas de investigaci\u00f3n que se han realizado, todas ellas relacionadas de alguna forma con la alimentaci\u00f3n de los pa\u00edses occidentales, son:<\/p>\n
<\/p>\n
1.-\u00a0 Consumo de leche descremada:<\/strong><\/p>\n El estudio prospectivo de Adebamowo y colaboradores\u00a0\u00a0 encontr\u00f3 asociaci\u00f3n positiva entre el consumo de leche descremada y acn\u00e9, en pacientes de sexo masculino de 9 a 15 a\u00f1os. Asimismo la investigaci\u00f3n de Adebamowo y colaboradores\u00a0 (20) Nurses Health study II concluyo que las mujeres que consumian mas leche en su adolescencia presentaban acne mas severo que los que no lo hacian. (21 , 25)Se plantea que el contenido hormonal de la\u00a0 leche (IGF-1, 5 alfa reductasa y alfa lactabumina) puede afectar la unidad pilosebacea<\/p>\n El consumo de leche estimular\u00eda una mayor secreci\u00f3n de insulina que aumentar\u00eda los niveles de IGF-1 Esto a su vez aumenta los andr\u00f3genos circulantes y la secreci\u00f3n seb\u00e1cea.<\/p>\n 2.- Consumo de hidratos de carbono refinados con alta carga glic\u00e9mica.<\/strong><\/p>\n Los hallazgos de Smith et al han demostrado que la dieta con hidratos de carbono con baja carga glic\u00e9mica disminuye las lesiones de acn\u00e9, mientras que los hidratos de carbono con alta carga glic\u00e9mica constituyen un fuerte est\u00edmulo para la secreci\u00f3n de insulina y de IGF-1.<\/p>\n El IGF-1 estimula la hiperqueratosis folicular y la secreci\u00f3n seb\u00e1cea, favoreciendo la patog\u00e9nesis del acn\u00e9 (22,24,26,27,29)<\/p>\n 3.-\u00a0 Consumo de grasas<\/strong><\/p>\n En el estudio prospectivo publicado en 1997 (8), se encontr\u00f3 que la ingesta de alta cantidad de grasas saturadas aumenta la concentraci\u00f3n de IGF-1, mientras que la alimentaci\u00f3n con baja grasa y mucha fibra tiende a disminuir la concentraci\u00f3n de IGF-1 y andr\u00f3genos y aumentar la concentraci\u00f3n de SHBG<\/p>\n 4.- Composici\u00f3n de \u00e1cidos grasos<\/strong><\/p>\n La relaci\u00f3n de omega- 6 a omega -3 de \u00e1cidos grasos de la dieta occidental es de 10:1, este omega -6 es un precursor de mediadores inflamatorios que aumentar\u00eda la secreci\u00f3n seb\u00e1cea y los andr\u00f3genos a nivel de la gl\u00e1ndula seb\u00e1cea, favoreciendo el desarrollo de acn\u00e9. Mientras que el omega- 3 ha sido encontrado que disminuye la IGF-1 y previene la hiperqueratinizaci\u00f3n del fol\u00edculo seb\u00e1ceo (11,12)<\/p>\n 5.- Chocolate<\/strong><\/p>\n Los trabajos de Grant, Anderson y Fulton (2,4,5) fueron realizados con una metodolog\u00eda que no puede establecer con una concluyente evidencia que una barra de chocolate puede o no tener alguna influencia en la producci\u00f3n del acne.<\/p>\n Algunas citas Bibliograficas colocadas en forma\u00a0 cronol\u00f3gica de los art\u00edculos publicados sobre Dieta y Acn\u00e9<\/p>\n 1956<\/p>\n 1.- Bourne JA. Observations on acne, seborrhea, and obesity. Br Med J 1956; 2: 1268\u20131270.<\/p>\n 1965<\/p>\n 2.- Grant JD, Anderson PC. Chocolate as a cause of acne: a dissenting view. MO Med 1965; 62: 459\u2013460.<\/p>\n 1967<\/p>\n 3.-Bett DG, Morland J, Yudkin J. Sugar consumption in acne vulgaris and seborrhoeic dermatitis. Br Med J 1967; 3: 153\u2013155.<\/p>\n 1969<\/p>\n 4.- Fulton EJ, Plewig G, Kligman AM. Effect of chocolate on acne vulgaris. J Am Med Assoc 1969; 210: 2071\u20132074.<\/p>\n 1971<\/p>\n 5.- Anderson PC. Foods as the cause of acne. Am Fam Physician 1971; 3: 102\u2013103.<\/p>\n 1991<\/p>\n 6.- Khanna NV, Pandhi RK, Bhutani LK, et al. Acne vulgaris and diet. Indian J Dermatol, Venereol, Leprol 1991; 57: 48.<\/p>\n 1995<\/p>\n 7.-Aizawa H, Niimura M. Elevated serum insulin-like growth factor-1 (IGF-1) levels in women with postadolescent acne. J Dermatol 1995; 22: 249\u2013252.<\/p>\n 1997<\/p>\n 8.- Lucky AW, Biro FM, Simbartl LA, et al. Predictors of severity of acne vulgaris in young adolescent girls: results of a five-year longitudinal study. J Pediatr 1997; 130: 30\u201339.<\/p>\n 9- Kaymak Y, Adisen E, Ilter N, et al. Dietary glycemic index and glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients<\/p>\n with acne. J Am Acad Dermatol 2007; 57: 819\u2013823.<\/p>\n 1998<\/p>\n 10.-.-White GM. Recent findings in the epidemiologic evidence, classification, and subtypes of acne vulgaris. J Am Acad Dermatol 1998; 39: S34\u2013S37.<\/p>\n 1999<\/p>\n 11.- Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr 1999; 70 (Suppl.): 560S\u2013569S.<\/p>\n 2000<\/p>\n 12.-James M, Gibson RA, Cleland LG. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 2000; 71 (Suppl.): 343S\u2013348S.<\/p>\n 2001<\/p>\n 13.-.-Kirk KM, Evans DM, Farthing B, et al. Genetic and environmental influences on acne in adolescent twins. Twin Res: Offic J Int Soc Twin Studies 2001; 4: 190.<\/p>\n 2002<\/p>\n 14.-Cordain L, Lindeberg S, Hurtado M, et al. Acne vulgaris: a disease of Western civilization. Arch Dermatol 2002; 138: 1584\u20131590.<\/p>\n 15.-Bataille V, Snieder H, MacGregor AJ, et al. The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. J Invest Dermatol<\/p>\n 2002; 119: 1317\u20131322.<\/p>\n 2003<\/p>\n 16.-Kaaks R, Bellati C, Venturelli E, et al. Effects of dietary intervention on IGF-1 and IGF-binding proteins, and related alterations in sex steroid metabolism: the Diet and<\/p>\n Androgens (DIANA) Randomised Trial. Eur J Clin Nutr 2003; 57: 1079\u20131088.<\/p>\n 2004<\/p>\n 17.-Wolf R, Matz H, Orion E. Acne and diet [review]. Clin Dermatol 2004; 22: 387\u2013393.<\/p>\n 2005<\/p>\n 18.-Bershad SV. Diet and acne–slim evidence, again. J Am Acad Dermatol. 2005 Dec; 53 (6):1102; author reply 1103.<\/p>\n 19.-Magin P, Pond D, Smith W, et al. A systematic review of the evidence for \u201cmyths and misconceptions\u201d in acne management: diet, face-washing and sunlight [review]. Fam<\/p>\n Pract 2005; 22: 62\u201370.<\/p>\n 20.-Adebamowo CA, Spiegelman D, Danby FW, et al. High school dietary intake and teenage acne. J Am Acad Dermatol 2005; 52: 207\u2013211.<\/p>\n 2006<\/p>\n 21.-Adebamowo C, Spiegelman D, Berkey CS, et al. Milk consumption and acne in adolescent girls. Dermatol Online J 2006; 12: 1\u201313.<\/p>\n 2007<\/p>\n 22.-Smith RN, Mann NJ, Braue A, M\u00e4kel\u00e4inen H, Varigos GA. The effect of a high-protein, low glycemic-load diet versus a conventional, high 23.-Kaymak Y, Adisen E, Ilter N, et al. Dietary glycemic index and glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients<\/p>\n with acne. J Am Acad Dermatol 2007; 57: 819\u2013823.<\/p>\n 24.-Smith RN, Mann NJ, Braue A, et al. A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. Am J Clin Nutr 2007; 86: 107\u2013115.<\/p>\n 2008<\/p>\n 25.-Adebamowo C, Spiegelman D, Berkey CS, et al. Milk consumption and acne in teenaged boys. J Am Acad Dermatol 2008; 58: 787\u2013793.<\/p>\n 26.-Smith RN, Braue A, Varigos G, et al. The effect of a low glycemic load diet on acne vulgaris and the fatty acid composition of skin surface triglycerides. J Dermatol Sci 2008; 50: 41\u201352.<\/p>\n 27.-Smith R, Mann N, M\u00e4kel\u00e4inen H, Roper J, Braue A, Varigos G.\u00a0 A pilot study to determine the short-term effects of a low glycemic load diet on hormonal markers of acne: a nonrandomized, parallel, controlled feeding trial. Mol Nutr Food ResJun;52(6):718-26, 2008.<\/p>\n \u202228.-Liepa GU, Sengupta A, Karsies D.. Polycystic ovary syndrome (PCOS) and other androgen excess-related conditions: can changes in dietary intake make a difference? Nutr Clin Pract. 2008 Feb;23(1):63-71<\/p>\n \u202229.-Smith R, Mann N, M\u00e4kel\u00e4inen H, Roper J, Braue A, Varigos G. A pilot study to determine the short-term effects of a low glycemic load diet 30.-Treloar V, Logan AC, Danby FW, Cordain L, Mann NJ. Comment on acne and glycemic index J Am Acad Dermatol. 2008 an;58(1):175-7.<\/p>\n 31.-Danby FW.\u00a0 Acne and diet. Ann Dermatol Venereol. Jan;135(1):9-11, 2008<\/p>\n 32.-Bodo Melnik Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societies JDDG; 2009<\/p>\n 2009<\/p>\n 33.- Elsa H. Spencer,, Hope R. Ferdowsian,, and Neal D. Barnard, Diet and acne: a review of the evidenceInternational Journal of Dermatology 2009, 48, 339\u2013347<\/p>\n Si desean el art\u00edculo complete (33), favor comunicarse con editores<\/p>\n","protected":false},"excerpt":{"rendered":" El art\u00edculo de \u201cElsa H. Spencer,, Hope R. Ferdowsian,, and Neal D. Barnard, Diet and acne: a review of the evidence International Journal of Dermatology 2009, 48, 339\u2013347\u201d, analizan las cinco grandes\u00a0 l\u00edneas de investigaci\u00f3n que se han realizado, todas ellas relacionadas de alguna forma con la alimentaci\u00f3n de los pa\u00edses occidentales, son:<\/p>\n","protected":false},"author":27,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[37],"tags":[],"class_list":["post-8329","post","type-post","status-publish","format-standard","","category-acne-y-enfermedades-relacionadas"],"_links":{"self":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/posts\/8329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/comments?post=8329"}],"version-history":[{"count":0,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/posts\/8329\/revisions"}],"wp:attachment":[{"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/media?parent=8329"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/categories?post=8329"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/piel-l.org\/blog\/wp-json\/wp\/v2\/tags?post=8329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial. J Am Acad Dermatol. Aug;57(2):247-56, 2007.<\/p>\n
\n on hormonal markers of acne: a nonrandomized, parallel, controlled feeding trial. Mol Nutr Food Res. 2008 Jun;52(6):718-26<\/p>\n