Systematically using antibioprophylaxis in dermatological surgery is not necessary Although antibioprophylaxis is not recommended in dermatological surgery, many dermatologists and plastic surgeons continue to prescribe an oral antibiotherapy after surgery of the skin, especially if the surgery is done on the nose or ear or if the reconstruction is done using flaps. A prospective study was done on 1000 patients who had had Mohs surgery for 1115 cutaneous lesions. There were only 8 surgical site infections (0.7%), 5 of which involved surgery of the nose. These infections affected 2.4% of flap reconstructions and 0.8% of Mohs surgery requiring multiple Mohs stages before reconstruction. These low rates of surgical site infections are conclusive evidence that antibioprophylaxis should not be used systematically. SLH Maragh et al. Prospective evaluation of surgical site infection rate among patients with Mohs micrographic surgery without the use of prophylactic antibiotics. J Am Acad Dermatol 2008;59:275-8.
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