An Update on Kaposi’s Sarcoma: Epidemiology, Pathogenesis and Treatment

Dermatol Ther (Heidelb). 2016 Dec;6(4):465-470. Epub 2016 Nov 1.
An Update on Kaposi’s Sarcoma: Epidemiology, Pathogenesis and Treatment.

Curtiss P1, Strazzulla LC1, Friedman-Kien AE2.

Abstract

Kaposi’s sarcoma is an angioproliferative neoplasm which has undergone considerable epidemiologic change since the original description by Moritz Kaposi in the late 1800s. This opportunistic neoplasm gained widespread notoriety within the US during the height of the AIDS epidemic, where it was frequently found co-occurring with opportunistic infections. With the advent of modern antiretroviral therapies, as well as an increasing number of individuals on immunosuppression for autoimmune disease or organ transplantation, the landscape of the immunocompromised individual has changed. It is now important for clinicians to be mindful of Kaposi’s sarcoma